This volume contains selected chapters on topics presented at the International Conference on Modeling, Analysis and Simulations of Multiscale Transport Phenomena (ICMASMTP 2022), held at the Department of Mathematics, Indian Institute of Technology Kharagpur, West Bengal, India, from 22–25 August 2022. It contains chapters on applications of porous media flow, diffusion–reaction equations, fluid dynamics, multi-scale analysis, electrokinetic transport processes, microfluidics modelling, numerical analysis, and related topics. Contributors are academicians, experts and researchers in various disciplines of applied mathematics, numerical analysis and scientific computation, having applications in physics, engineering, chemistry, biology and medical science.